How I Boosted Testosterone And Reduced Estrogen With A Regimen Of Progesterone, Pregnenolone, Dhea, And D-Aspartic Acid

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Editor’s Note: This is a guest post from David Mills.

Hi I’m David

Three and a half years ago I was diagnosed with low testosterone. I had man boobs, I was overweight, I had low energy, and my libido sucked. In this article I’d like to share with you how I used 100% natural methods to boost my testosterone levels by more than 280% in a matter of months. Not only did I get rid of my man boobs, but I’m also in great physical shape, I’m full of energy, and at age 63, I feel better than I have in decades!

Three and a half years ago my testosterone was just 155 ng/dl (normal reference range 348-1200 ng/dl). My estrogen levels where also high, with estradiol at 46 pg/ml (normal reference range being 7.6-42.6 pg/ml). My doctor put me on weekly testosterone shots, which gave me some nasty side effects. After many months of extensive research and experimentation, I finally managed to find some all-natural alternatives that work just as well as my doctor’s prescription testosterone, yet without the nasty side effects.

I have now been off testosterone supplementation of any kind for sixteen months. At almost 64 years of age, my testosterone checked last month at a whooping 590 ng/dl, and my estradiol at just 10.5 pg/ml. Let me repeat; I am at 590 ng/dl not taking any testosterone. My testosterone increased from 155 to 590 and my estradiol decreased from 46 to 10.5. My testosterone/estradiol ratio was 3.36 to 1 before I started any kind of treatment. It is now 56.2 to 1.

4 Natural Remedies That Skyrocketed My Testosterone

Here‘s how I did it. I take four things to boost my testosterone and decrease my estrogen. All four can be bought over the counter; no prescription is necessary. Here is my regimen for the last twelve months:

(1)   Topical progesterone – 60 mg a day;

(2)   Pregnenolone (progesterone’s precursor) – 100 mg capsules every other day;

(3)   DHEA – 25 mg pill once a week,

(4)   D-Aspartic acid – between 1,500 and 2,000 mg per day (usually comes in a capsule of 500mg or 750 mg).

How I Discovered This Powerful Regimen

The main reason I had low testosterone was due to low levels of leutenizing hormone (LH). Low LH happens to many men. LH is the hormone the pituitary gland in your brain makes to tell your testicles they need to make testosterone. I was making only 2.0 mIU/L of LH, when the reference range is 2-10 mIU/L.

My internist sent me for a CAT scan to rule out a tumor in my pituitary gland. Thankfully, the scan results were negative. I had no tumor, but I also had no answer for my low LH levels. Apparently some men get low LH without any identifiable reason. So I asked my internist if there was anything I could take to raise my LH levels, but he didn’t know. He had not heard of D-Aspartic acid and was unaware of recent studies showing that D-Aspartic Acid increases LH.

The only solution my internist had for me was testosterone shots. I took these and they worked. My energy increased, my strength increased, and I had a substantial improvement in mood.

The greatest benefit was to my back. At the age of 48, I had a lumbar disc removed and my back had been in constant knots ever since. I had five or six golf ball sized knots in my lower back. I called them the “iron cross”. Twelve years of an iron cross across my back just disappeared on high levels of testosterone. It was amazing. Testosterone is a steroid after all, and it worked on my back as well as Medrol dose packs (hydrocortisone). I could only take Medrol dose packs a couple times a year and they would help for a couple of days; but testosterone was magic. I could have shots every week and the knots pretty much stayed away.

However, these high levels of testosterone (mine got as high as 1250 ng/dl at one point) also had some unpleasant side effects…

The Nasty Side-Effects Of Artificial Testosterone

The only way to safely boost testosterone is to increase your body’s own natural production of the hormone. The trouble with external testosterone shots is that your body converts all the excess testosterone into estrogen. It does this using the enzyme aromatase.

After just 10 weeks on testosterone shots, my estrogen increased from 46 to 86 pg/ml. I soon got gynecomastia (man boobs) and a shrunken testicle sac (felt like my balls wanted to ascend to my abdomen). I also gained 15 pounds in a couple of weeks.

My doctor put me on an aromatase inhibitor to lower my estrogen, but I didn’t feel it was helping. I was also suffering from another common side effect of external testosterone supplementation, called polycythemia. This is where your body produces more blood cells and your blood gets thicker. It can lead to heart attacks, strokes, hypertension, and countless other life-threatening conditions. I learned that many people have to stop taking testosterone because of this condition.

The Testosterone Alternative That Flattened My Man Boobs Almost Overnight

I was not at all happy with the idea of taking an aromatase inhibitor (aromatase inhibitors are highly toxic and one of my doctors flat told me to throw it out), so I started taking progesterone to see if it would work on my man boobs.

Progesterone is the body’s natural aromatase inhibitor. It also opposes estrogen. Taking 30 mg of progesterone a day reduced my estrogen from 86 to 30 pg/ml. It worked literally overnight to cure my gynecomastia and shrunken testicle sac. So I said goodbye to prescription aromatase inhibitors and began using progesterone to reduce my estrogen levels. I started taking progesterone two and a half years ago for my man boobs and still take it to this day.

I was astounded by my discovery that progesterone could reduce estrogen so effectively.

But this paled in comparison to what I discovered next (and did so completely by accident).

Here's what happened.

The ups and downs you get from weekly testosterone shots can drive you crazy. Thirty hours after a shot, testosterone peaks; and thereafter it begins a steady decline.  Ten days later you are back to baseline.

Taking a daily topical gel stops the ups and downs, so my doctor put me on testosterone gels; but the gels didn’t work nearly as well as the shots. After six months on gels, my testosterone level was back in the 200 range and taking large amounts of gel only got me to 350 or so.  The gels did help my back but not nearly as good as the shots.

In the end I decided to get back on the shots, but to do so, I would have to come off the gel to establish my baseline testosterone levels.

As I feared, soon after I stopped taking testosterone altogether, my back pain started to come back. And here's where the magic happened…

I increased my progesterone dose to 60 mg to see if its anti-inflammatory properties could rival that of testosterone. To my surprise, it did! Progesterone worked just as well as my old testosterone shots.

When I went for my next hormone test, I was fully expecting to have testosterone levels of 150 ng/dl again (since I had stopped taking testosterone); but to my surprise, it was about 350 ng/dl, and all thanks to progesterone!

Progesterone had somehow boosted my body’s internal production of testosterone, which as I mentioned earlier, is the best way to boost testosterone safely and without side effects.

So How Did I End Up Adding Pregnenolone, DHEA, And D-Aspartic Acid To My Progesterone Regimen?

Since adding these to my regimen, my testosterone has gone from 350 ng/dl (on progesterone alone) to an impressive 590 ng/dl! I was not satisfied with 350 and wanted to see if I could get it higher.

Here’s how I did it.

On doing some research online, I discovered that D-Aspartic acid can raise LH levels – something my doctor was NOT aware of. In fact, it was the bodybuilding community that taught me this (it turns out bodybuilders know more about testosterone than most MD’s). When the study showing D-Aspartic acid raises testosterone came out, the bodybuilders were all over it. So I wanted to try it to see what it would do.

The problem was that D-Aspartic acid taken alone could deplete your testosterone precursors. Just to be on the safe side, I thought I should have testosterone precursors in reserve. The three primary precursors of testosterone are progesterone, pregnenolone and DHEA. These three precursors were also listed in a scientific article as a means of reducing cholesterol if you returned them (along with testosterone) to “youthful” levels. Since my cholesterol was on the high side, it made sense to try all of them, plus I had literature supporting the idea of taking them.

I figured if I took reasonable, safe doses of these three testosterone precursors, I could safely take D-Aspartic acid and not worry about running out of testosterone precursor reserves.

So I started adding in pregnenolone, DHEA, and D-Aspartic acid to my progesterone regimen. I decided to take very little DHEA because of concerns about its use in higher doses (I take 25 mg of DHEA a week instead of the 25 mg a day recommended on the bottle).

The amount of pregnenolone I decided to take was based on recommendations by Dr. Ray Peat. I settled on 60 mg a day of progesterone, though even higher doses of progesterone had been recommended to me by Wray Whyte, the owner of progesteronetherapy.com, who had been running the site for 15 years. She convinced me that several hundred milligrams a day of progesterone was safe, partly due to the fact that as fetuses, we are floating in a placenta making 400 mg of it a day during the third trimester of pregnancy.

As for how much D–Apartic acid I take, I started at a lower dose than what is recommended on the bottle. The bottle lists a daily dose of 3,000 mg a day and I decided to take 1,500-2,000 mg a day. As of last month, my LH is now 3 mIU/L, which is up from the 2 mIU/L I had three and a half years ago.

Tweaking the Regimen Even More

Now that I have my latest results, I recently bumped up my D-Aspartic acid to 3,000 mg a day instead of the 1,500–2,000 mg I was taking before. If I can get my LH to 4 or 5 maybe I can get my testosterone back up to 700 or so, which is my target. I am feeling pretty good right now, so who knows, I might already be in the 700 range – my next test will tell.

Safety and Benefits of the Regimen

I have now been on a regimen of 60 mg of topical progesterone, 100 mg of pregnenolone capsules every other day, 25 mg of DHEA a week and at least 1,500-2,000 mg a day of D-Aspartic acid for twelve months with zero side effects and excellent lab results. I also lost the 15 pounds I gained from my testosterone shots.

All of these substances are known to be very safe, with the possible exception of DHEA in high doses (which is why I take a much lower dose than recommended on the bottle).

The studies are all clear on the safety of progesterone, pregnenolone, and D-Aspartic acid in high doses. In one study, subjects took 2,660 mg of D-Aspartic acid daily for 90 days. Not only did they experience significantly higher testosterone levels and increased fertility, researchers also noted no serum abnormalities and no side-effects.

Just for good measure, and because Wray Whyte highly recommended it to me, I also take 6,000 units of Vitamin D a day to keep my Vitamin D levels up. Vitamin D is more of a hormone than a vitamin and it has a symbiotic relationship with progesterone.

So What Have You Got to Lose?

I welcome anyone to try my regimen, but if you do, I would caution everyone to get their hormone levels tested regularly. Getting tested may seem expensive, but since you’ll only be doing it every six months or so, it really isn’t that bad.

Where Is The Best Place To Get These Supplements?

I have looked all over the internet searching for the best deals on these products. Seeing that they have restored my testosterone levels, along with my youth and vitality, the fact that I pay just 50 bucks a month for all four of these supplements, seems like a total steal.

Here is where I have found the best prices and best quality.

I buy progesterone and prognenolone from a place called Supplementspot.com. I get the progesterone gel in the pump bottle; and each pump is very consistent in delivering 15 mg of progesterone per pump (so I take 4 pumps a day).

It's important, by the way, to only ever get bioidentical hormones, as these are closer to nature and studies have shown that they are safer and more effective than their synthetic counterparts.

I get my DHEA from Walgreen's.

I buy D–Aspartic acid on Amazon. I use a brand called “Finaflex Pure Test”, but since I am increasing my daily dosage I just bought a brand called “Hard Rhino D Aspartic acid”.

If you are interested in learning more, I have told Garry I would be glad to write more about progesterone, pregnenolone, and testosterone; including their relationship to cholesterol (they all come from the LDL “bad” cholesterol — for which I took statins and which ironically may have contributed to my low testosterone). I have been studying this stuff almost daily for the last three and a half years and am glad to share what I have learned. Your thoughts, comments and questions are welcome.

 


David Mills is a retired personal injury attorney with a keen interest in medicine. Over the 35 years he spent in this career, he has amassed a team of reliable medical experts he can consult at any time.

David has had a lifelong influence from medicine. His father (deceased) taught medical and graduate school for 40 years. His brother, with a PhD in biophysics, has spent 30 years doing human biochemical and medical university research. His wife is a registered nurse.


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225 thoughts on “How I Boosted Testosterone And Reduced Estrogen With A Regimen Of Progesterone, Pregnenolone, Dhea, And D-Aspartic Acid”

  1. Very motivating info. I’m now 70 years of age with good total T numbers but extremely low free T numbers. My estrogen level is also way high (70). What would be a reasonable dosage of progesterone to start with. Also, where do you apply the topical cream and do you change application areas.
    Thanks much,
    JR
    Arizona

  2. Hello, been reading through all the comments, thank you for the very useful information. Has there been any update on the protocol’ any new blood work?

    thank you.

  3. Hello, my question is about male pattern baldness. Western medicine states that MPB is due to high levels of DHT. To western medicine that is the only cause. In my opinion it is only one piece of a large complex puzzle. IMO one of the major culprits of MPB is low thyriod and estrogen. I am a 41 year old male and I am starting to lose my hair. Like most men it is a very scary situation to be facing. So I have been doing alot of research on MPB (Male Pattern Baldness). I have come to the conclusion that one of the huge missing pieces of the puzzle is progesterone. It increases testosterone in men which is key. Lowers estrogen which is key. Inhibits DHT levels and strengthens the thyroid gland. My question to you is can I be supplementing a very low dose of progesterone cream daily on my skin for the rest of my life without a blood test? To me the status quo of what normal levels of hormones various too much with people. What average for most might be different for me. What happens if progesterone is too high? Thanks for your time.

  4. Hi David

    I was wondering what danger you were wanting to avoid by taking too much DHEA. I have been reading a book about DHEA by Stephen Cherniske called “The DHEA Breakthrough”. In this he talks about people in their 60’s (which I am 62) taking between 50-75 MG of DHEA a day. I realize his book was written in the 90’s so are you aware of information that suggests DHEA might not be safe at those levels? Actually, I have been taking 25 mg. a day but skipping a day every 5 days or so. Do you think even that is too much?

    I have already been using some D-Ascorbic Acid and have been using a product called D-Poll but I have been a little afraid that it might lead to an increase in Estrogen, so I took a break from it for a while. I didn’t see any evidence of increased estrogen in the month or so that I was taking it, but didn’t know if it could happen.

    I am going to try your protocol (adding the progesterone and progenilone??? (on the spelling) and see if I can get my testosterone back up. I have lots of energy and I exercise very faithfully so, I must have some Testosterone going on, but I have sure had difficulty in the ED department. That is my main concern. I am assuming it is a Testosterone problem. I am very happily married to my wife for 41 years. I weigh 158 lbs and I am 6 foot tall. I don’t have any issues with the man boobs problem but I sure don’t want to see a high estrogen problem develop.

    So, I am assuming that you have figured out that your protocol will build Testosterone and not Estrogen. Is that accurate?

    I do appreciate being able to talk to you about all this. thanks for making that possible.

    Thank you for getting back on some of these thoughts and question.

    Gary

  5. Like you, I am over 60 and have excellent Total T levels (960) but my Free T sucks at 7.4. SHBG is very high at 165. Estrodial was at 22. I’ve recently taken Stinging Nettle Root extract and my Total T went to 1000, Free T to 12.5 and SHBG dropped to 115, and Extradiol increased to 33. Should I increase my dose of Nettle (currently 500mg/day) to bring down the SHBG further? Then, what do I do to limit the increase in Estradiol?

    Steve

  6. Sunil. Sorry, I guess I was confused about your numbers. 178 is low, very low. For some reason I had thought it was around 1200 and I was wondering what you were complaining about. I would think you would see improvement in several weeks time. Since you are that low I would do 60mg a day. Let us know if this helps.

    • Thanks David, I will keep you posted, however can you pls reply to me on my personal email so that I can share some more personal issues with you regarding the hormone deficiancy. I am still awaiting my order, they seem to be taking too long for the delivery. It has been more than a week since I ordered and paid.

  7. As for application, put it anywhere on your body. Best to move it around. As for how long it will take to see results, I don’t know since your T levels and E levels were very good. Progesterone is a regulator. Conceivably, your T levels are too high and it might reduce them. On the other hand, nobody really knows what T levels should be since they declined by 15% after the first round of testing on a large population (1950’s era) after about 15-20 years and then declined another 15% another generation later. So I don’t know what it will do in your case. Let us know.

    As to whether to start out high or low, I think I would start low and build up.

    • Hi again David, I did some research to find out conversion of my blood results to match with your units, I found that my Estradiol was at 57.24pmol/L which equals to 15.5910pg/mL, Total T was at 6.2nmol/L which equals to 178.82ng/dL (which is too low); and Free T was at 9.2pg/mL (ref is 8-54pg/mL) that is like on the lower side according to the references. Pls elaborate and advice again. Thanks

  8. Hi David, I have ordered 3bottles of progesterone cream and 1 bottle (90caps) of pregenolene from supplementspot on 16jan. I hope to receive the order by next week. should I start with your dose of 60mg or should I start with lower dose and work my way up?? and how to apply and where on the body. I believe pregnenolene is 1 cap per day?? how long do I use before I can see results?? Thanks

  9. Thanks David, what is your take after Garry’s comment on the units of measurement? You did not comment on the T-levels??
    Also I have sent another email to Garry regarding the Natural Progesterone Cream that I found from the Supplementspot.com site. I have attached a photo of the item for you to confirm if it is ok so then I can order it with the pregnenolene from the same place. Also please give me an indication of dosage. Thanks once again.

  10. Sunil. It looks like your estradiol is way to high unless this is a different scale of measurement than I am used to. Gary would know better than I. So if he confirms that your estradiol is way too high, then progesterone and pregnenolone will help get it back to normal levels. DHEA is not likely to work by itself. Your LH seems quite in the normal range (again if the scale of measurement is the one we normally use) so it is probably not necessary to take D-Aspartic acid to boost LH.

    • Hi David, thanks for replying to Sunil’s comment.

      The unit of measurement for estradiol most of us are used to is pg/ml. Sunil’s lab has used pmol/l. At the lab I’m looking at right now, the reference ranges for estradiol are as follows:

      13-42 pg/ml = 48-154 pmol/L

      Sunil provided LH in mIU/L, for which the reference range is 1.8-12.0 mIU/L.

  11. Hi David, Still awaiting you response to my question 3 days ago, however in the meantime I was browsing the supplementspot.com page where I found the ‘Natural Progesterone Cream’ but it states it is mostly for women. Will also appreciate your instruction on which is the right one to get. Thanks

    • Don’t worry about it being “mostly for women.” Men need progesterone too to keep the proper estradiol – testosterone -progesterone balance. You want balance at “youthful levels.” And youthful levels of testosterone, DHEA and progesterone have been reported to reduce cholesterol levels.

  12. Hi David, thanks of very informative article. I had some blood work done last week results were – Total T @ 6.2nmol/L; Free T @ 9.6pg/mL; Estradiol E2 @ 57.24pmol/L; and LH @ 5.49 mlu/ml. I would appreciate your comments. Similar to your back pain I also suffer from arthritis and more so on my hip joint which has been very painful. I had seen a holistic naturapath and she recommended I take 5000iu of Vit D3 with 25mg of DHEA. Been on it for a few months but not helping that much. I would like to try your regimen hence would like to get your comments before I order the supplements. I would highly appreciate an urgent reply to this. Thanks

  13. Hi David,

    Thank you for your very informative article.

    I’m a 46 yo male. I’ve been supplementing with pregnenolone 50mg/daily and DHEA 25mg/daily for the past 6 months. I also take 2 Fish Oil caps, 1000iu of vitamin D and 400mg of Magnesium. I’ve lost 8% of my body weight and feel really good.

    I just had a blood test done and total free testosterone is 1270. However, my LDL cholesterol came in at 232. It has never been this high and has always been around 140. I was really surprised as I thought higher testosterone levels should lower LDL.

    Approximately 10 weeks prior to my blood test, I changed my diet such that I removed all processed grains (bread, rice, pasta), potatoes and eliminated sugar. I also eliminated most dairy, except for hard cheese. I eat plenty of fruit, vegetables and nuts.

    I’d be interested in your thoughts on what has caused the spike in LDL. Could it be from my preg/dhea supplementation? Do you have any suggestions on how I can lower it without resorting to the 10mg of rosuvastatin I’ve been prescribed?

    Thanks for your feedback,

    Sol

    • That is a very high testosterone number. What was it before? Remember this LDL is the precursor of Pregnenolone, which is the precursor of progesterone, which is the precursor of testosterone. If LDL levels are low you are going to have difficulty with making these hormones.

      More importantly, what is the LDL/HDL ratio?

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