Calcium-D-Glucarate: The New Wonder Supplement That Knocks Estrogen Out Of Your Body And Helps Get Rid Of Man Boobs

Calcium-d-glucarate is particularly powerful at helping you to lose man boobs because it’s really good at lowering estrogen levels in your body.

Why Lowering Estrogen Is A MUST If You Want To Lose Your Man Boobs

Man boobs are becoming more and more common in the modern day because we are all exposed to artificial estrogens called “xenoestrogens”.

We get exposed to xenoestrogens from pesticides, plastics, vehicle exhaust fumes, emulsifiers in soaps and cosmetics, and even through contaminations in our drinking water.

Xenoestrogens aren't just responsible for you having man boobs. A lot of research suggests that estrogen dominance is an important cause of today's obesity epidemic. If you are overweight, then estrogen is likely to blame.

Not only does estrogen encourage fat storage, it also opposes anabolic hormones like testosterone, which are needed for muscle growth. So if you find it harder to grow muscle than other guys do, then estrogen again is likely to blame.

Excess estrogen is also responsible for a plethora of illnesses that are becoming more and more common over time as we are exposed to more and more chemicals in our food, water, cosmetics and environment.

Examples of other problems caused by xenoestrogens include breast and prostate cancer, decreased fertility, heart disease and diabetes.

Not only can calcium-d-glucarate help you lose man boobs, lose body fat and grow muscle by reducing estrogen levels in your body, it can also help you fight cancer, reverse diabetes, decrease LDL cholesterol, assist in protein digestion, and remove toxins from your body.

Calcium-D-Glucarate Flushes Estrogen Out Of Your Body

One of the most common treatments for high estrogen levels is a drug called tamoxifen.

The trouble with tamoxifen is it has numerous side effects including stroke, blood clots, uterine cancer, and cataracts.

New research is showing that calcium-d-glucarate could be just as effective as Tamoxifen in treating estrogen dominance. What’s really cool is unlike tamoxifen, this all-natural supplement has no known side-effects!

A review in 2003 said calcium-d-glucarate could be as effective in preventing cancer as tamoxifen.

In one study, calcium-d-glucarate was able to reduce the number of estrogen receptors by 48 percent. It’s also been shown to lower serum estrogen levels by 23 percent!

How Calcium-D-Glucarate Works

One of the ways the body gets rid of toxins like xenoestrogens, is through a process called conjugation.

During conjugation, toxins are packaged into water soluble compounds in the liver. They then pass from the liver to the gut where they are excreted.

However, high levels of an enzyme called beta-glucuronidase can inhibit this process.

This enzyme separates toxins from their conjugate bond and allows them to be reabsorbed back into the body.

This allows toxins to keep circulating in the body where they make you fat, tired, and weak.

Calcium-d-glucarate works by inhibiting beta-glucuronidase. It keeps the toxins bound in their conjugated form so they can be removed from the body.

Toxins are most damaging in their free form, which is why you want them to be bound (conjugated) and released from the body.

About Calcium-D-Glucarate

We all produce a small amount of calcium-d-glucarate in our bodies naturally.

We also get small amounts of calcium-d-glucarate by eating fruits and vegetables.

Early humans were able to get enough calcium-d-glucarate from their own production since they had access to more nutritionally dense food and lived in a clean, toxin-free environment.

As toxin exposure has increased in the modern day, we need more calcium-d-glucarate to excrete the extra toxins.

However, the human body is only capable of producing small amounts of this compound, so the only way to keep up with the modern day’s unnaturally high toxic load on our bodies, is by taking calcium-d-glucarate supplements.

How Much Calcium-D-Glucarate Should You Take?

Studies show that the effect of a single low dose can last for up to 5 hours. So the best way to take calcium-d-glucarate is by taking at least two split doses—one in the morning and the other in the evening. Ideally, if your schedule permits, you’d do better to take four split doses, leaving only 6 hours between each dose.

For a normal detox dose, take 500-1,000 mg a day. So if taking 1000 mg a day, you’ll take 500 mg in the morning and 500 mg in the evening. Or you can take 250 mg every six hours (i.e. four times a day).

Keeping in mind that calcium-d-glucarate is more effective at higher doses, and has been reported to be side-effect free and safe even at 10 times the recommended dose, it is recommended that you take a higher dose if you have a particular problem that needs solving. If you have man boobs or, say, cancer resulting from estrogen dominance, then take 1,000 to 2,000 mg a day. You can even take as high as 3,000-4,500 mg a day.

Side Effects And Drug Interactions

Your liver breaks down calcium-d-glucarate to get rid of it. Alcohol may decrease the effectiveness of calcium-d-glucarate by increasing how fast the body gets rid of it.

Some medications are broken down and eliminated by the liver. Calcium-d-glucarate may speed up this process, thereby decreasing the effectiveness of these medications. You can see a list of possible intereactions in WebMD here.

What’s A Good Calcium-D-Glucarate Supplement?

Where you can, I only ever recommend taking supplements that contain no artificial fillers or additives.

I typed “calcium-d-glucarate” into, went through the first two pages of results, and picked out the few supplements that don’t contain any potentially harmful fillers or additives.

Calcium-D-Glucarate Supplements That Contain No Artificial Fillers Or Additives:

These are quite expensive. You get what you pay for I guess.

More Affordable Options With Minimal Additives:

Combine Calcium-D-Glucarate With This Supplement For A One-Two Knockout Punch Against Estrogen Dominance And Man Boobs

Calcium-d-glucarate works particularly well when combined with another supplement that I have mentioned to you before.

This other supplement is just as powerful as calcium-d-glucarate, if not more.

Both supplements put a dead-halt stop to the havoc excess estrogen wreaks on your body. They work well together because they inhibit estrogen via COMPLETELY different mechanisms.

While calcium-d-glucarate ensures estrogen stays bound in its conjugated form, so it can be excreted from the body, this other supplement does two totally different things:

  1. It inhibits the enzyme aromatase, which is the main source of estrogen in the male body. Aromatase converts the male hormone testosterone into estrogen.
  2. It acts on more potent forms of estrogen (e.g. 16-hydroxy estrogens) and converts them into less potent forms (2-hydroxy estrogens) that actually have a beneficial affect on your body.

So while calcium-d-glucarate helps excrete excess estrogen, this other supplement reduces the production of estrogen and helps convert the more potent forms of estrogen into less potent, healthy forms of estrogen.

This other supplement is called diindolylmethane (“DIM” for short).

Here’s a good DIM supplement with excellent ratings, that contains no artificial fillers or additives:

What Are Some Good Food Sources Of Calcium-D-Glucarate?

The highest concentrations of calcium-d-glucarate are found in grapefruits, apples, oranges, and cruciferous vegetables.

I’d be slightly cautious of grapefruit though. Some studies suggest it may elevate estrogen levels via other mechanisms. Though the data is inconclusive, with some studies showing it does no such thing, it’s best limit your intake of this fruit.

Stick to apples, oranges and those crucifers.

Here’s a list of cruciferous vegetables:

  • Arugula
  • Bok choy
  • Broccoli
  • Brussels sprouts
  • Cabbage
  • Cauliflower
  • Chinese cabbage
  • Collard greens
  • Daikon radish
  • Horseradish
  • Kale
  • Kohlrabi
  • Land cress
  • Mustard greens
  • Radish
  • Rutabaga
  • Shepherd's purse
  • Turnip
  • Watercress

You’ll find a more comprehensive list in Wikipedia here.

If you remember, in How To Lose Man Boobs Naturally, I mentioned that cruciferous veggies are also the best source of DIM.


Calcium-d-glucarate has a powerful effect on helping to reduce those estrogen levels, and it’s proven by science.

By taking this one supplement, you not only reduce estrogen, thereby making it easier to lose your man boobs, lose weight and grow muscle, but you also decrease your risk of cancer, remove toxins from your body, ensure healthy liver function, and lower your LDL and total cholesterol levels.

It’s a perfectly natural supplement that has no known side-effects, and you can take it alongside other supplements like DIM to really kill that reign estrogen has on your body.