Study Shows Obese Men Lack This Important Hormone

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In a 2006 study published in the journal, Hormone and Metabolic Research1, researchers looked at progesterone levels in obese vs. lean men.

They concluded that,

“Plasma progesterone was negatively associated with markers of obesity such as BMI, waist circumference and subcutaneous adipocyte diameter in this sample of men”.

So the more body fat the subject had, the lower the level of progesterone. The less body fat the subject had, the higher the level of progesterone.

Progesterone isn’t nearly as well studied as something popular like testosterone, so the researchers mention they don’t know whether low progesterone resulted in obesity, or obesity resulted in low progesterone in these men.

We know that with testosterone it works both ways:

  • If you get fat, your testosterone level will go down.
  • If you’re already fat and you boost your testosterone levels, your body fat levels will go down.

We’ll need further studies to know for SURE if low progesterone can make you fat, and more importantly, if boosting progesterone using a natural progesterone cream can make you lose fat and get lean, but knowing about the properties of progesterone, it’s quite clear that progesterone, much like testosterone, can help you get lean.

Progesterone inhibits estrogen, it’s a precursor for testosterone, it inhibits the enzyme aromatase which converts testosterone to estrogen.

So the take-home message from this study is this:

If you are overweight, then reducing your weight will help boost progesterone levels. Higher progesterone levels are associated with improved sleep, improved fertility, a stronger immune system, stronger bones, reduced heart disease risk, a better cholesterol profile, and protection against cancer.

Also, if you are overweight, supplementing with progesterone may help you to lose weight.

If you do supplement with progesterone, make sure you only use a natural USP bioidentical progesterone like this one. The synthetic progestins most doctors prescribe have a long list of nasty side-effects.

Also, most progesterone creams on the market are made for women. Make sure you choose one that’s specifically designed for men, since men generally need lower doses of progesterone than do women.

Here’s a good men’s progesterone cream with the right dose, containing natural USP bioidentical progesterone, and other ingredients in the right proportions to ensure the progesterone is absorbed through your skin, and has a positive effect on your body:

What’s great about using a good men’s progesterone cream, is not only is it likely to help you lose weight, but it could also help you lose man boobs, thanks to its role as an estrogen antagonist.


  1. Blanchette, S., Marceau, P., Biron, S., Brochu, G. & Tchernof, A. Circulating progesterone and obesity in men. Horm Metab Res 38, 330-335, doi:10.1055/s-2006-925392 (2006).

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